<i>Lhermitte-Duclos disease</i>

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Lhermitte - duclos Disease :

Lhermitte-Duclos disease (LDD) is a benign neoplasm of posterior fossa, involving cerebellum. It is also known as dysplastic cerebellar gangliocytoma. It is not a true neoplasm but a hamartoma. It can be either isolated finding or associated with Cowden (multiple hamartoma syndrome). adults.

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Lhermitte-Duclos disease.

Lhermitte-Duclos disease was first described in 1920 in the literature under the names of Purkinjeoma, granular cell hypertrophy of the cerebellum, hamartoma of the cerebellum, dysplastic gangliocytoma, ganglioneuroma, and gangliomatosis of the cerebellum. Patients tend to be young adults and may present with signs of cerebellar dysfunction or increased intracranial pressure secondary to obstru...

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Lhermitte-Duclos disease.

Lhermitte-Duclos disease (dysplastic gangliocytoma of the cerebellum) is a rare benign cerebellar mass of unknown etiology which is characterized by enlargement of the cerebellar folia. Despite the controversy regarding its pathogenesis, imaging and histopathological findings are rather typical. A 17-year-old female presented with a 2-year history of progressive headaches and gait imbalance. Cr...

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Lhermitte-Duclos disease and pregnancy

Dysplastic cerebellar gangliocytoma (Lhermitte-Duclos disease) is a rare disorder, characterized by a slowly progressive unilateral neoplastic mass of the cerebellar cortex. The histopathological findings of LhermitteDuclos disease (LDD) include the widening of the molecular layer, which is occupied by abnormal ganglion cells, absence of the Purkinje cell layer and hypertrophy of the granulan c...

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Lhermitte-duclos Disease in a Young Adult Case Report

Dysplastic gangliocytoma of the cerebellum is a very rare lesion. The other names assigned to this pathology are Lhermitte-Duclos disease. ganglioneuroma. hamartoma of the cerebellum. purkengioma. granule cell hypertrophy or granulomolecular hypertrophy of the cerebellum. Only few cases have been reported in the literature (1-20).since the first report by Lhermitte and Duclos (11).Clinically. t...

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ژورنال

عنوان ژورنال: Neurology India

سال: 2008

ISSN: 0028-3886

DOI: 10.4103/0028-3886.44811